23 Responses to “A Cure for Rheumatoid Arthritis in Mice: BIM”
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That would be great if I didn’t have to poison my body to get rid of this disease!
Someday! We’ve already come so far in our lifetime. It’s a happy thought, isn’t it?
I sure agree, Krista. I’ve tried for years to avoid taking the drugs. Unfortunately, so many heath issues are handled by drugs that can potentially harm us or even cause death. I wish there were better alternatives. It would be miraculous if this new research allows us to start living normal lives again.
“Start living normal lives again…” I think it would depend on the patient. 75% of the mice had their RA halted. But previous damage from RA would not be erased. Then there is the other 25% – I’m sure they are asking why it did not cure them. RA is so complicated & maddening, isn’t it?
Still, it’s hopeful to see that they are looking for cures.
It will be better for our children/ grandchildren…
What an encouraging thought!! I am actually so pleased to hear that thus far there has been no adverse recations by the mice! This is so very hopeful! Thank you Kelly for sharing this exciting news.
~Theresa
I’ve read about this potential treatment, and also others in the works. I’ve read in so mnay different places that we are literally about 10 years from a cure…Lots of researchers are arriving at exciting points in the hopes of curing RA, and they are metting every year to discuss their findings. In some cases, they are finding that one set of research can aid another. Thus, many believe the cure is already out there, and it is being developed as I type this. In fact, there is a dr. with a blog who does nothing on his blog but summarizes the newest RA research. He says he does this b/c we are on the verge of a cure, and he wants to document it.
Is he right? Are they all? I’m not sure. I want to believe it, but I’m also like Kelly…even if they do cure it, how much of my life will I get back at this point? And for me, the cure would come just as I was exiting the phase where I may want to conceive and raise another child. Seems unfair…but then again, so much about this disease is unfair.
From what I’ve heard ten years is not even close. It will be a long time.
BUT!! It’s still not how it was for my grandad or Mary Lee…
It’s sad to say…the article/results were submitted in February 2009, accepted in October 2009 and finally published in February 2010. Make you wonder what’s been happening with this for the last year! Have any clinical trials started? Any preliminary information available? (I doubt it.)
Kevin, that is the reason it took me half a day to do this little post. It was so confounding.
This stuff can be infuriatingly slow – a year between submission and publication is quite common, actually. The people who reviewed the paper want editing and often whole new experiments, so it’s a process! It does seem like something that could be an exciting new therapy, but it would probably still be something that patients have to take long term. But any new treatment is huge for patients who don’t get relief from the current therapies! There’s a lot more testing to do before clinical trials, but I can almost guarantee that they’re thinking of it!
Thank you. So many people get discouraged and start to say that there is no one searching for RA cures / better treatments. As I read many postings of this BIM molecule across the net, I was shocked at reader comments people left on the articles. They claimed that the FDA or pharmaceutical companies are “hiding” real cures so that they can continue to make billions from Biologics. It’s good to hear the other side.
Encouraging and scary all at the same time. As much as I would love nothing better than to have this RA cured, I don’t know if I’d be a willing participant in this clinical trial (if and when it comes about). Call me paranoid, but it caused me great anxiety just reading about it – what if this BIM interacted with a person’s individual body chemistry and went on a rampage killing off too many immune cells. Would that put us into a stage like AIDS (with no immune system left)? Sorry, just expressing my thoughts…..
Oops – forgot to click on the Notification button – I’m interested to hear what others think about this new development.
Important point. I’m probably not going first in any trial either…
Sounds great and I don’t mean to seem like a pessimist but I have to wonder how this would reverse the damage done to joints, undoing damage already done seems like pipe dreaming to me.
No, Bud. As I commented to Marina above, I do not think previous damage that occured could all be reversed. Very good point. Getting RA diagnosed & treated early will always be the most important thing. Better treatments will help, but not turn back time. This would be a way to stop the progression and inflammation.
I had similar thoughts, Doreen. Call me paranoid, but I would be afraid to have little nanotech suicide bomber thingies injected into my body, unless they were THOROUGHLY tested and proven already. Kinda sounds like a scifi movie – “Revenge of the Nanobombers.”
Thanks for the update Kel. There are also safety issues related to nanoparticles themselves.
What a fantastic miracle that would be!!
Lets hope that this is the real deal for RA and we wil see a “cure”! Thanks Kelly.
Thanks Kelly! I hope this works. I pray for everyone with this.
Kelly, Northwestern University is in the same town that I was born and raised
I lived about 2 miles from NWU. And as always…. awesome post 
Thanks for this…very exciting!