The Post

Comments (5)


5 Responses to “Safe Acetaminophen Dosage with Chronic Pain”

    1. Jim Logajan says:

      I would like to suggest that anyone taking acetaminophen or methotrexate consider also taking Resveratrol because the latter has shown to protect the liver in studies on rodents. A search of Google (or Google Scholar) for the keywords “reserveratrol acetaminophen” yields links to article abstracts such as:

      http://www.sciencedirect.com/science/article/pii/S1386634606000477
      http://www.sciencedirect.com/science/article/pii/S0378427415001617
      http://www.sciencedirect.com/science/article/pii/S0278691515001234
      http://onlinelibrary.wiley.com/doi/10.1002/jat.1249/full

      Keywords “reserveratrol methotrexate” yielded, among others, these papers:

      https://ejournals.library.ualberta.ca/index.php/JPPS/article/view/7920
      http://journals.sagepub.com/doi/abs/10.1177/0960327112468178
      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4565222/

      It seems resveratrol is generally protective of the liver, as indicated by this study which fed rats a liver toxin, carbon tetrachloride, and found it helped protect the rat livers:

      http://onlinelibrary.wiley.com/doi/10.1002/jat.1249/full

    2. Catherine says:

      It’s funny because I prefer Ibropuen and find it works better except for Excedrin migraine which really helps my headaches. I am very careful and tend to only take pain meds when absolutely necessary which basically means I’m always in pain.

    3. Marla Nolan says:

      Kelly, its safer to limit to 2g or 2000mg.. I have taken MTX for 28 years and the only increase in liver enzymes I’ve had was when I took 4000mg. Went off and the came back down. Now I limit and no problems.

    4. Deborah Kelly says:

      Tylenol has zero effect on my pain.

    5. Helen Pohl says:

      I don’t take aspirin or Tylenol but my legs are full of bruises! My Dr says it’s nothing but it bothers me. Anyone have any answers?

    The Post

    Comments (5)


    What do you think?


    Would You Like Free Email Updates?
    Stay in touch with RA Warrior.
    We respect your privacy. Your email address will never be shared.