I would like to suggest that anyone taking acetaminophen or methotrexate consider also taking Resveratrol because the latter has shown to protect the liver in studies on rodents. A search of Google (or Google Scholar) for the keywords “reserveratrol acetaminophen” yields links to article abstracts such as:
It seems resveratrol is generally protective of the liver, as indicated by this study which fed rats a liver toxin, carbon tetrachloride, and found it helped protect the rat livers:
It’s funny because I prefer Ibropuen and find it works better except for Excedrin migraine which really helps my headaches. I am very careful and tend to only take pain meds when absolutely necessary which basically means I’m always in pain.
Kelly, its safer to limit to 2g or 2000mg.. I have taken MTX for 28 years and the only increase in liver enzymes I’ve had was when I took 4000mg. Went off and the came back down. Now I limit and no problems.
I would like to suggest that anyone taking acetaminophen or methotrexate consider also taking Resveratrol because the latter has shown to protect the liver in studies on rodents. A search of Google (or Google Scholar) for the keywords “reserveratrol acetaminophen” yields links to article abstracts such as:
http://www.sciencedirect.com/science/article/pii/S1386634606000477
http://www.sciencedirect.com/science/article/pii/S0378427415001617
http://www.sciencedirect.com/science/article/pii/S0278691515001234
http://onlinelibrary.wiley.com/doi/10.1002/jat.1249/full
Keywords “reserveratrol methotrexate” yielded, among others, these papers:
https://ejournals.library.ualberta.ca/index.php/JPPS/article/view/7920
http://journals.sagepub.com/doi/abs/10.1177/0960327112468178
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4565222/
It seems resveratrol is generally protective of the liver, as indicated by this study which fed rats a liver toxin, carbon tetrachloride, and found it helped protect the rat livers:
http://onlinelibrary.wiley.com/doi/10.1002/jat.1249/full
It’s funny because I prefer Ibropuen and find it works better except for Excedrin migraine which really helps my headaches. I am very careful and tend to only take pain meds when absolutely necessary which basically means I’m always in pain.
Kelly, its safer to limit to 2g or 2000mg.. I have taken MTX for 28 years and the only increase in liver enzymes I’ve had was when I took 4000mg. Went off and the came back down. Now I limit and no problems.
Tylenol has zero effect on my pain.
I don’t take aspirin or Tylenol but my legs are full of bruises! My Dr says it’s nothing but it bothers me. Anyone have any answers?