Methotrexate Archives | Rheumatoid Arthritis Warrior

Prevent RA Just Like Cancer

Could methotrexate prevent RA? Several studies presented at the American College of Rheumatology’s (ACR) Annual Scientific Meeting in Chicago last fall are investigating how to prevent RA. One poster in particular, from the Netherlands’ group, presented startling results as they re-analyzed data from the PROMPT trial. They concluded that a one-year course of methotrexate could prevent RA or delay its development.1 I...Continue reading      7 Comments » Read more

Remaining Pain with Rheumatoid Arthritis Treatment

A common problem: remaining pain with Rheumatoid Arthritis Remaining pain with Rheumatoid Arthritis (RA) has been a topic on RAW since 2009. We've discussed how people manage the common “leftover” symptoms such pain, fatigue, and stiffness while being treated for rheumatoid disease. Leftover or remaining pain is the subject of an interesting abstract reported at the recent...Continue reading      30 Comments » Read more

Efficacy of Xeljanz, Biologics, & DMARDs in Rheumatoid Disease

Why should I feel like I failed? I’m not alone We probably agree it’s unfair to say, “patients fail treatments” instead of the reverse, but there is still disappointment. I was optimistic that my Rheumatoid disease would respond to Xeljanz, the new oral DMARD (disease modifying anti-rheumatic drug) from Pfizer. Unfortunately, my joint stiffness and inflammation,...Continue reading      44 Comments » Read more

New England Compounding Center and Beyond: Medications Warnings and Dangers

When there are warnings of dangers related to medication, there is greater risk to chronic disease patients for two reasons: First, we may be more likely to use the drugs in question. And second, we are more vulnerable because we have a systemic illness. Several news reports over the past few weeks are especially relevant...Continue reading      8 Comments » Read more

The End of the Methotrexate Shortage, Thanks to Pfizer?

Pfizer addresses U.S. methotrexate shortage that hurts RA patients Earlier this year the FDA approved an abbreviated new drug application, securing Pfizer’s right to sell injectable methotrexate in the U.S. Recently, Pfizer says they began shipping to customers. This move by Pfizer addresses an urgent shortage of methotrexate in the U.S. that has affected many Rheumatoid...Continue reading      21 Comments » Read more

RA News: Pfizer Pill Beats Methotrexate, Alcohol Reduces RA Risk, Periodontal Disease High

Pfizer oral JAK “superior” to methotrexate Pfizer released a statement about their two year study, ORAL Start, which puts their new oral JAK treatment for Rheumatoid Arthritis directly up against methotrexate.  The oral medication, currently called tofacitinib, is taken twice daily in either 5 or 10 mg doses. “Tofacitinib was found to be superior to MTX...Continue reading      9 Comments » Read more

Confusion & Blame Surround Methotrexate Shortages & Recalls

U.S. caught off guard by methotrexate shortage Shortages of injectable methotrexate began in 2010 and some sources say may continue through 2014. Many have been surprised that shortages of such inexpensive generic drugs could take Americans by surprise and continue for such an indefinite period. Finger-pointing at the FDA and drug companies is probably the one...Continue reading      41 Comments » Read more
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