Unusual Methotrexate Side Effects

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Many patients take low enough doses of methotrexate that they don’t even have side effects…

But, some strange methotrexate side effects are for real

methotrexate pillsNo one ever told me methotrexate could have side effects. I’m not complaining! I think that worked for me. I didn’t approach the treatment with fear.

Don’t get me wrong – there was drama. But it was based on other things: Wean your baby. Swallow these pills for the rest of your life. Hope it helps you walk. Give up occasional beer and wine

Without any fears of methotrexate side effects, I didn’t set myself up for failure. I didn’t have to worry about whether the side effects were partially psychosomatic or not. I was more likely to talk myself out of side effects than into them. And more likely to give the treatment a chance to work.

What are some weird methotrexate side effects?

This is not about the common side effects like nausea and minor hair loss. There are some more odd side effects of methotrexate that have either been described to me or I’ve encountered myself. I have not had all these myself, but the ones that I did have were not until my dose reached the maximum amount for my body mass.

  • Metallic taste
  • Breast tenderness
  • Menstrual changes
  • Mood changes
  • Lower GI cramping
  • Brain fog
  • Rashes or blisters

Some methotrexate weird side effects probably aren’t

I don’t think that I’ve ever seen an Oxford Journal abstract titled Weird Methotrexate Side Effects, have you? But patients talk about it. There are plenty of places online where you can find some pretty extreme lists of side effects. Some are more realistic than others.

It can be difficult to isolate which medicine is responsible for which side effect. Often prednisone is to blame. But don’t rule out the Rheumatoid Arthritis itself. Going off of treatment when RA is flaring can make it obvious many problems are actually caused by the RA.

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Kelly Young. All rights reserved.

This entry was posted on Thursday, August 12th, 2010 at 6:00 am and is filed under Treating RA. You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site.


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