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What is Sjogren’s Syndrome?

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Rheumatoid arthritis and sjogrens syndrome 

What Rheumatoid Arthritis does have to do with Sjogren’s Syndrome ?

Often we mention the “characteristic dry eyes of RA.” However, we have more urgent concerns of our Rheumatoid Arthritis. This may be one reason that we don’t know much more about Sjogren’s. We have often accepted dry eyes as just one more Rheumatoid Arthritis symptom without exploring it further.  

What is it?

Sjogren’s syndrome is an autoimmune disorder in which the lymph (immune) system attacks the exocrine (excreting) glands. It is characterized primarily by dry eyes and dry mouth. About half of the time, Sjogren’s occurs with Rheumatoid Arthritis or other rheumatoid diseases; this is Secondary Sjogren’s. However, Sjogren’s can appear alone; then it is Primary Sjogren’s. Sjogren’s incidence is about 90% female.

What will I notice?

Patients may not be aware that their tear ducts are less operational until they experience itching, burning, redness, or sensitivity to light. By then, Sjogren’s has attacked the tear glands and begun to damage the cornea. With regard to the mouth, patients might first notice lip dryness or difficulty swallowing dry foods. Often, there is a constant urge to drink something or put something like a mint into the mouth.

Why should I care?

Rheumatoid Arthritis has most of us pretty well trained to never complain. We don’t want one more roll of the eyes. And we don’t need one more doctor’s appointment on our calendar. To us, having dry eyes is a less significant problem than others we routinely face. For these reasons, we may not get treated for a problem which may be readily treatable. It is also important that we know a bit about Sjogren’s because we should be monitored carefully for the more perilous symptoms. The rarer symptoms are serious, but usually treatable. 

What are the symptoms of Sjogren’s?

Common symptoms of Sjogren’s include eye dryness leading to eye infections and erosions of the cornea which may be experienced as a “glare” sensation; mouth dryness may lead to cavities since antibacterial saliva is reduced; gastric hyperacidity because the body also uses saliva to neutralize stomach acid; depression; sleep disruptions; severe fatigue; arthritis and arthralgia symptoms (muscle and joint pain and weakness); nasal and upper respiratory dryness.
  
Less common symptoms include involvement of skin (rashes), lungs, heart, pancreas, kidneys, liver, spleen, and lymph nodes. Joints, nerves, or muscles can become inflamed. There is also damage which can occur wherever mucous has been reduced by affected glands. For example, nasal dryness may cause nosebleeds and trachea damage can lead to respiratory infections. Damage to lung tissues can lead to pneumonia.

How is Sjogren’s diagnosed?

Sometimes the same blood tests which indicate other auto-immune diseases are used to indicate Sjogren’s, such as ANA, ESR, or Rf. However, some simple office tests can be used to get a more specific indication. There is a crude filter paper test in which a doctor uses paper to measure the moisture on the surface of the eye. A slit lamp exam provides a magnified 3-d scan of the eye, revealing damage caused by dryness. The Rose Bengal test makes dry spots and mucous abnormalities visible by applying a food dye to the eye. If necessary, more elaborate tests such as biopsies or x-rays can be done.

How is Sjogren’s treated?

There is no cure. Heard that one before, haven’t you? Often, the same DMARDs used to treat Rheumatoid Arthritis are used to prevent disease progression and to control inflammation in Sjogren’s syndrome. Additionally, there are lots of options to deal with the “leftovers.” Most of the symptoms of Sjogren’s do have effective treatments.

Listen to a doctor’s advice:

“Although it sounds rather frightening that Sjogren’s can affect other parts of the body, it is important to recognize that each of these problems is responsive to therapy if detected early and treated adequately. It is equally important to recognize that SS patients are not exempt from other common problems that may occur in these age groups. Thus, it is unfortunately too common that a treatable problem was delayed in diagnosis since the symptom was incorrectly attributed to SS. For example, the same symptoms in any other patient might have been readily diagnosed as a routine pneumonia, gall bladder stone, kidney stone or ectopic pregnancy,” ( from dry.org, Drs. Fox and Michelson).

In case you were wondering, Sjogren’s is pronounced “show grins.” I always said RA’ers were good-natured folk. :D

Detailed overview of Sjogren’s at emedicine.

Recommended reading:

My Quest for Answers to Questions About Rheumatoid Arthritis
Some Answers for Rheumatoid Arthritis Just Bring More Questions
Ankylosing Spondylitis and Rheumatoid Arthritis

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Kelly Young. All rights reserved.

This entry was posted on Friday, July 10th, 2009 at 1:24 pm and is filed under RA Education. You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site.

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