RA Research, Resources, and Rheumatology Archives | Page 7 of 11 | Rheumatoid Arthritis Warrior

A Methotrexate Alternative for Rheumatoid Arthritis?

This molecule has “the potential to further improve the most successful principle of folate inhibition in the treatment” of Rheumatoid Arthritis. Folate antagonism has been the foundation of treatment for Rheumatoid Arthritis for almost two decades. Methotrexate is used to inhibit the proliferation of inflammatory cells, probably at least in part by folate antagonism. There are...Continue reading      30 Comments » Read more

Rheumatoid Arthritis Rheumors: 2 Mysteries Solved

I thought it was brilliant the other day when a commenter called RA “the ghost disease.” It’s true that many RA myths persist and that researchers don’t yet know exactly how Rheumatoid Arthritis works. Which joints can be affected? Is there a nutritional cure that we are overlooking?   Confusion about RA is perpetuated in plenty...Continue reading      32 Comments » Read more

Evidenced-based Medicine or Easy-bake Oven: Tension Between Evidence and Reality

This post was inspired by the article Patient Advocates: Flies in the Ointment of Evidenced Based Care by Jessie Gruman at Health Affairs Blog. Patient advocacy and evidenced-based medicine are both intimately entwined with several matters in rheumatological care, but first a word about flies. Patient advocates probably are flies in the ointment, and there would...Continue reading      35 Comments » Read more

An Introduction to the Genetics of Rheumatoid Arthritis (RA)

RA Genetics 101: Glass half-full or half-empty? Part 1 Please welcome Professor Robert W. West, Jr, PhD as a guest on the subject of Rheumatoid Arthritis and genetics. Professor West uses his expertise in genetics to teach Personalized Medicine and other courses to the doctors of the 21st Century. A recent article on Ankylosing Spondylitis (AS) illustrates...Continue reading      19 Comments » Read more

Santa, Bring Her a Rheumatologist Please

Wanted: good rheumatologists Sonya’s tweet brought me a smile. So much truth in so few words. Those of us with rheum diseases like RA need a good doctor the way most people need a reliable car mechanic. We might crash and burn without it. This is short for two reasons: 1) I don’t have a long list of...Continue reading      57 Comments » Read more

ACR REF Rheum Research & Courage That Won’t Back Down

“Hey baby, there ain’t no easy way out… I won’t back down.” We just got back from Miami from the ACR Research Education Foundation (REF) RA Investigators’ Meeting where important research topics were discussed such as Lung disease of RA – our 2nd leading cause of death Rheumatoid heart disease research Porphyromonas gingivalis and the pathogenesis of Rheumatoid Arthritis On...Continue reading      11 Comments » Read more

ACR’s Research Education Foundation Investigators’ Meeting

REF RA researchers focus on progress The American College of Rheumatology’s Research Education Foundation has gathered over 50 researchers from across the U.S. to present their data from the Within Our Reach RA studies. They’ll be brainstorming ways to collaborate in finding a cure for RA. The meeting will feature a wide range of RA research topics that...Continue reading      4 Comments » Read more

Using CRP in Criteria for Rheumatoid Arthritis Clinical Trials

To people with an incurable disease, clinical trials signify the possibility of a cure. Perhaps my suffering will end one day. Someone is looking for answers. Someday my prince will come. Research matters to patients Most patients I know read with interest headlines about their disease. They trust medications that have been recommended to them because of effectiveness...Continue reading      47 Comments » Read more

Rheumatoid (Arthritis) Heart Disease

Most webpages about Rheumatoid Arthritis (RA) will tell you that you can reduce your risk for heart disease by eating healthy and reducing lipid levels. That’s seems instinctive for people to believe. However, evidence does not support it. Do lipids matter with Rheumatoid heart disease? The famous Red Dress Campaign for heart disease awareness in women lists...Continue reading      20 Comments » Read more

A Spoonful of Sugar from the Lab of Professor Rebecca Bader

Katie Beth and I were on the road again this past week! We drove down to a Disney convention center to see the castles and other fantastic things like dreams come true… Mission of Bader Research Laboratory Rebecca Bader, Assistant Professor of Biomedical & Chemical Engineering at the Syracuse Biomaterials Institute of Syracuse University and her staff are...Continue reading      6 Comments » Read more

Tofacitinib / CP-690550 aka Tasocitinib Succeeds in Pfizer’s 2nd Phase 3 Trial

A new name and new milestone for tofacitinib Pfizer announced Friday that CP-690550 tofacitinib (formerly tasocitinib) met its goals in its second phase three clinical trial for moderate to severe Rheumatoid Arthritis. Tofacitinib is a JAK 3 inhibitor, an oral treatment for RA with a different approach than current Biologic RA treatments. According to Pfizer, over 4,000...Continue reading      14 Comments » Read more

Susceptibility for Rheumatoid Arthritis Acquired via Microchimerism?

Women with RA ask why it’s so common to acquire severe Rheumatoid Arthritis after pregnancy the way I did. I don’t blame my son since my symptoms went back years, but these studies are fascinating… Rheumatoid Arthritis HLA shared epitope may be acquired in pregnancy The current issue of Arthritis and Rheumatism brings a study which concludes...Continue reading      24 Comments » Read more
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