New Way to Report Response in RA Clinical Trials?

August 23, 2011May 15, 2018 Kelly Young 15 Comments American College of Rheumatology, Rheumatoid Arthritis Clinical Trials, Unrelenting RA - Persistent disease, XELJANZ-tofacitinib-JAK

Untangling a possible replacement for the “familiar” ACR 20 describing treatment response in clinical trials for Rheumatoid Arthritis Special thanks to Jay Sprinkel for assistance with this post. Although he may be more known for the humor he provides to our Facebook group, Jay is a retired marine biologist who specializes in statistics. He is also...Continue reading 15 Comments » Read more

Tofacitinib / CP-690550 aka Tasocitinib Succeeds in Pfizer’s 2nd Phase 3 Trial

March 9, 2011May 15, 2018 Kelly Young 14 Comments Rheumatoid Arthritis Clinical Trials, Rheumatoid arthritis treatment, XELJANZ-tofacitinib-JAK

A new name and new milestone for tofacitinib Pfizer announced Friday that CP-690550 tofacitinib (formerly tasocitinib) met its goals in its second phase three clinical trial for moderate to severe Rheumatoid Arthritis. Tofacitinib is a JAK 3 inhibitor, an oral treatment for RA with a different approach than current Biologic RA treatments. According to Pfizer, over 4,000...Continue reading 14 Comments » Read more

Rheumatoid Arthritis Drug Trials for Tasocitinib aka CP-690550

March 25, 2010May 15, 2018 Kelly Young 27 Comments Rheumatoid arthritis treatment, XELJANZ-tofacitinib-JAK

Phase 3 Rheumatoid Arthritis drug trials mean more widespread testing of Tasocitinib aka CP-690550 Last night, I learned some exciting news about a new kind of Rheumatoid Arthritis drug in development called Tasocitinib. Tasocitinib is administered in a pill form. However, it is being compared to Biologics which are administered intravenously or injected. Tasocitinib, also known as...Continue reading 27 Comments » Read more

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