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Loading ... Loading ...4 thoughts on “Rheumatoid Arthritis Research Using Marmosets as Subjects”
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We have long needed better animal models for several diseases. The marmoset provides many good opportunities for meaningful and significant research. BUT – the Marmoset is not a perfect model, and some studies will not be fruitful. This is why we will always need studies in human populations.
Nevertheless, I am very pleased that there is a better animal model for in vivo studies. I hope that many good facts can be learned and good leads for earlier detection and treatments will be found.
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Testing on animals. Something I find distasteful. Making another living thing suffer. Nope. Seems wrong to trade torturing an animal for my own health problems.
For the marmoset model to take off it would have to demonstrate that it is superior in its prediction of human efficacy over other, more established models. There are numerous logistical challenges with using nonhuman primates over mice and rats. Different housing and animal care and use protocols. Not to mention the cost and availability of marmosets. I would say that most of these challenges and others would make it prohibitive for its use in lead optimization.