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On the alcohol study—now I know why my RA didn’t bother me much from age 21 thru about age 29. LOL.
hehe. good to know. and for me, I was busy nursing babies during those yrs which is supposed to ward of RA as well. So of course I drank little or never and I’ll never know if it could’ve helped protect me.
Great article Kelly. I am very familiar with the JAX protocols. These are very important to Pfizer as they were originally targeted on psoriatic arthritis. I would imagine an entire team of colleagues on working on the FDA response. The FDA has begun to ask more and more for responses due to the potential for suicidal ideations with many new compounds in the CNS and inflamatory response specialties. Here’s hoping this is another alternative for us beside MTX. MTX and I had a very short time together due to severe migraines and my rhemy not believing in treating the migraines. Still on sulfazaladine and now CIMZIA. Hoping for big things!
thanks, we’ve been following the JAK & a couple more in the pipeline for a while. I know several folks have found JAK a big help but then I also have met a couple of people who get remission from mtx. Individual differences, what I call our “immune fingerprint” are what make this so tough. Some may have bad reactions to these, but others will have lives saved. My goal is to explain that the disease itself is dangerous enough that for many patients, the risks of the disease outweigh the risks of the tx.
Amen on that! I am trying most anything right now that my rheumy suggests….sorry I meant JAK (my former boss would get me on that typo as these were in his portfolio of studies). The pain is so intense sometimes….inside and out. I took the big step on Saturday. My hair was just falling out in huge clumps so I bought a wig a week ago but Saturday…my hair stylist took the scissors and cut it all off (what didn’t fall out in her hand). Surprisingly all is still ok, the sun came up this morning and I am still walking!
Thanks again Kelly.
I finally found a dentist 5 yrs ago who didn’t treat my dental problems like they were my fault. He also explained that some of my meds caused dry mouth and so my teeth were more likely to get cavities / gums to get sore / more tartar buildup / etc. Such a relief to have a dentist understand, and for me to stop blaming myself!
Re: the alcohol findings. Since stress is a factor in RA, I wonder if the women who drank more than 4 times a week long term felt less stressed and therefore perhaps delayed or avoided onset of RA. Just a random thought.
My rheum was involved in this JAK study. He submitted me for it, but I was rejected. I think because I wasn’t in “enough” pain. I hope they get it approved soon because I would like to try it and I know he will put me on it. I am very close to firing him, but I think I will hold off until this is approved.
Alcohol…it figures. I HATE alcohol. I did read a book on RA from the late 1800’s and the doctor (in the UK) talked about giving his patients “bitter beer” and seeing them recover from the brink of death to normal, productive lives.
Champagne always makes me feel more festive!!
However when on med’s not such a good idea.