A new study proves what many suspected – that Rheumatoid Arthritis patients develop antibodies against adalimumab (Humira) which lessen the effectiveness of the drug. Previous studies have shown this to be true for other Biologic treatments as well. Anti-adalimumab antibodies: another front in our battle against RA Doctors in the Netherlands found 28% of patients developed antibodies...Continue reading      35 Comments » Read more

Rheumatoid Arthritis patients will likely try a sequence of 3 or 4 biological therapies. However, odds tend to decrease that the treatments will work. “For patients with prior exposure to TNF-a inhibitors, likelihood of response to subsequent treatment with biologic agents declines with increasing number of previous treatments with TNF-a inhibitors.” Newsflash: responses to Biologic treatments vary...Continue reading      32 Comments » Read more

It’s been too long since I told an elephant joke. When I was little, I carried this book around making the adults miserable. Why stop now? Q. Why is an elephant large, gray, and wrinkly? (Answer below post.) How long do Rheumatoid Arthritis patients stick with Biologics? There is a lot of variation about when to change Biologics...Continue reading      63 Comments » Read more